pCBRG- C/EBPα RE
CBV20066
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| Introduction | |
| Description: | pC/EBPα RE-Luc is designed for monitoring the induction of CCAAT/enhancer-binding protein alpha.The transcription factor CCAAT enhancer-binding protein α (C/EBPα) is a tumor suppressor in myeloid cells and inhibits proliferation in all cell types examined.C/EBPα regulates genes involved in differentiation of the liver, gut, skin, adipose tissue, and in the myelomonocytic lineage of the hematopoietic system . In addition, C/EBPα is a powerful inhibitor of proliferation in all cell types reported to date, including virally transformed or tumorigenic cell lines that lack various tumor suppressor proteins . Loss of C/EBPα functions have been linked to leukemogenesis, suggesting an important role for C/EBPα as a tumor suppressor |
| Plasmid profile: |  |
| Unit Size: | 1-4μg |
| Pathway (Activitor): | CCAAT/enhancer-binding protein alpha |
| Pathway profile: |  |
| Full Name: | CCAAT/enhancer-binding protein alpha |
| Cis response element: | C/EBPα RE |
| Shelf Life: | One year from date of receipt under proper storage conditions. |
| Storage: | -20°C |
| Mode of transportation: | Ice bag transport |
| Matters needing attention: | For your health, please wear lab clothes and disposable gloves. |
