CD40L Target Cell
CBP74335
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| I. Background | |
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CD40 是腫瘤壞死因子受體超家族（TNFRSF）成員，作為免疫調節的關(guān)鍵分子，廣泛 參與 B 細胞活化、抗原呈遞細胞（APC）成熟及 T 細胞免疫應答。其配體 CD40L（CD154） 主要表達于活化的 T 細胞，通過(guò) CD40-CD40L 互作橋接先天性與適應性免疫，是腫瘤免疫 治療、自身免疫病及感染性疾病的熱門(mén)靶點(diǎn)。 |
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| II. Description | |
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CD40L Target Cell，穩定表達人 CD40L。 |
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| III. Introduction | |
| Expressed gene: | CD40L |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS +1μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
IV. Representative Data Figure 1. Recombinant CD40L Target Cell stably expressing CD40L.  Figure 2. Blocking of CD40L induced Activity by CD40L Blocking Ab in CD40 NFκB-Luc HEK293 Cell(C4) with CD40L Target Cell(C7). |
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