Panel-Ref? EGFR Cocktail II 5% Reference Standard
CBP90006
詢(xún) 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數據庫
| Introduction | |||||||
| Format | Genomic DNA | ||||||
| Description | 包含EGFR常見(jiàn)突變的5個(gè)突變，適用于評估EGFR相關(guān)的檢測，作為質(zhì)控品、參考品等。 | ||||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF | Chr position (GRCh37) | |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 5% | chr7:55242466_55242480 | |
| EGFR | p.G719A | c.2156G>A | 18 | COSM6239 | 5% | chr7:55241708 | |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 20 | COSM12376 | 5% | chr7:55249010_55249011 | |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 5% | chr7:55249091 | |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 5% | chr7:55259524 | |
| Product Information | |||||||
| Intended Use | Research Use Only | ||||||
| Unit Size | 1ug/vial * 1 vial | ||||||
| Concentration | Download for COA | ||||||
| Purity | Download for COA | ||||||
| DNA electrophoresis | Download for COA | ||||||
| Storage | 2-8°C | ||||||
| Expiry | 36 months from the date of manufacture | ||||||
| 如下表是EGFR常見(jiàn)的突變位點(diǎn)，我們可以按照您的需求定制EGFR Panel，或者定制其中沒(méi)有的位點(diǎn) | |||||||
| Gene | AA Change | CDS Change | Exon | Cosmic ID | AF% | Chr position (GRCh37) | |
| EGFR | p.C797S | c.2389T>A | 20 | COSM6493937 | 50% | chr7:55249091 | |
| EGFR | p.C797S | c.2390G>C | 20 | COSM5945664 | Coming soon | chr7:55249092 | |
| EGFR | p.T790M | c.2369C>T | 20 | COSM6240 | 50% | chr7:55249071 | |
| EGFR | p.L861Q | c.2582T>A | 21 | COSM6213 | 100% | chr7:55259524 | |
| EGFR | p.V769_D770insASV | c.2307_2308ins GCCAGCGTG | 19 | COSM12376 | 100% | chr7:55249010_55249011 | |
| EGFR | p.E746_A750delELREA | c.2235_2249del15 GGAATTAAGAGAAGC>- | 19 | COSM6223 | 100% | chr7:55242465_55242479 | |
| EGFR | p.E746_A750delELREA | c.2236_2250del15 GAATTAAGAGAAGCA>- | 19 | COSM6225 | 50% | chr7:55242466_55242480 | |
| EGFR | p.L747_A750>P | c.2239_2248TTAAGAGAAG>C | 19 | COSM12382 | 100% | chr7:55242469_55242478 | |
| EGFR | p.G719A | c.2156G>C | 18 | COSM6239 | 100% | chr7:55241708 | |
| EGFR | p.G719S | c.2155G>A | 18 | COSM6252 | 33.33% | chr7:55241707 | |
| EGFR | p.G719C | c.2155G>T | 18 | COSM6253 | Coming soon | chr7:55241707 | |
| EGFR | p.S768I | c.2303G>T | 20 | COSM6241 | 100% | chr7:55249005 | |
| EGFR | p.A763_Y764insFQEA | c.2290_2291ins tccaggaagcct | 19 | COSM26720 | 100% | chr7:55248992_55248993 | |
| EGFR | p.H773 V774insNPH | c.2319_2320ins AACCCCCAC | 20 | COSM12381 | 100% | chr7:55249021_55249022 | |
| EGFR | p.D770_N771insSVD | c.2311_2312ins GCGTGGACA | 20 | COSM13428 | 100% | chr7:55249013..55249014 | |
| EGFR | p.L858R | c.2573T>G | 21 | COSM6224 | 50% | chr7:55259515 | |
| EGFR | p.L747_P753>S | c.2240_2257del18 TAAGAGAAGCAACATCTC | 19 | COSM12370 | 100% | chr7:55242470_55242487 | |
