MET Loss Reference Standard
CBP40058
詢(xún) 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數據庫
| Introduction | ||
| Format | Genomic DNA | |
| Description | MET, MET proto-oncogene, receptor tyrosine kinase, is a receptor tyrosine kinase, which activates MAPK, PI3K/AKT, SRC, and STAT pathways to promote cell proliferation, invasion, and angiogenesis (PMID: 22128285). MET mutations, exon 14 skipping mutations (PMID: 31369639), and fusions have been identified in a variety of human cancers (PMID: 28603720), including lung cancer (PMID: 32273721), and MET amplification and/or overexpression has been reported in many solid tumors, including biliary tract cancer (PMID: 32085275), breast cancer (PMID: 31991499, PMID: 31892551, PMID: 32234363), NSCLC (PMID: 31832192), gastric cancer (PMID: 31499745), intrahepatic cholangiocarcinoma (PMID: 32089411), and gallbladder carcinoma (PMID: 31645095). | |
| Technical Data | ||
| Copy number | 1 | |
| Definition | Loss | |
| Product Information | ||
| Intended Use | Research Use Only | |
| Unit Size | 1ug | |
| Concentration | Download for COA | |
| Purity | Download for COA | |
| DNA electrophoresis | Download for COA | |
| Sanger sequencing | Download for COA | |
| Storage | 2-8℃ | |
| Expiry | 36 months from the date of manufacture | |
